Provided is a seal for sealing the esophagus of a slaughtered animal such as a cow, the constituent parts of such a seal and a device and a method for sealing the esophagus of a slaughtered animal, such as a cow, by arranging such a seal. The seal comprises a cylindrical body which can be placed in the esophagus and is provided with a cylindrical peripheral wall with an end wall, a clamping element which can be displaced to a clamping position relative to the body for clamping oesophageal tissue between at least a part of the clamping element and the cylindrical body, thus fixing the seal in the esophagus and thereby sealing the esophagus, wherein the peripheral wall encloses a receiving space and is provided with an opening through which oesophageal tissue can be carried into the receiving space and is there clamped fixedly by the clamping element.