An apparatus and method for determining the apparent intima-media thickness (IMT) of arteries through acquisition and analysis of ultrasound images comprising an array of pixel intensities. A datum, or datums, may be established across multiple columns of pixels bounding the portion of the image containing either the lumen/intima boundary, the media/adventitia boundary, or both. The datums may be approximate the shape of one more of the lumen, intima, media, and adventitia. Within a bounded portion of the image, a method may search for intensity gradients having characteristics indicating the gradients represent probable locations of the lumen/intima and media/adventitia boundaries. An IMT measurement is calculated based on the location of the lumen/intima and media/adventitia boundaries. An IMT measurement may be adjusted for sloping or tapering of an artery wall.