Invention Grant
US08771664B2 Compositions comprising apolipoprotein A polypeptide and interleukin 15, and methods of treatment using the same
有权
包含载脂蛋白A多肽和白介素15的组合物，以及使用其的治疗方法
- Patent Title: Compositions comprising apolipoprotein A polypeptide and interleukin 15, and methods of treatment using the same
- Patent Title (中): 包含载脂蛋白A多肽和白介素15的组合物，以及使用其的治疗方法
-
Application No.: US13514855Application Date: 2010-12-10
-
Publication No.: US08771664B2Publication Date: 2014-07-08
- Inventor: Pedro Berraondo Lopez , Jessica Fioravanti , Jose Medina Echeverz , Ignacio Javier Melero Bermejo , Maria del Carmen Ochoa Nieto , Francisco de Asis Palazon Garcia , Silvia Bulfone-Paus , Erwin Hans Duitmann
- Applicant: Pedro Berraondo Lopez , Jessica Fioravanti , Jose Medina Echeverz , Ignacio Javier Melero Bermejo , Maria del Carmen Ochoa Nieto , Francisco de Asis Palazon Garcia , Silvia Bulfone-Paus , Erwin Hans Duitmann
- Applicant Address: ES Pamplona (Navarra) DE Borstel
- Assignee: Fundacion para la Investigacion Medica Aplicada,Research Center Borstel
- Current Assignee: Fundacion para la Investigacion Medica Aplicada,Research Center Borstel
- Current Assignee Address: ES Pamplona (Navarra) DE Borstel
- Agency: Hoffmann & Baron, LLP
- Priority: ES200931158 20091211; ES201030813 20100527
- International Application: PCT/ES2010/070818 WO 20101210
- International Announcement: WO2011/070214 WO 20110616
- Main IPC: A61K38/20
- IPC: A61K38/20 ; C07H21/04 ; C07K14/54 ; C07K14/775 ; C12N5/00 ; C12P21/02
Abstract:
The present invention relates to compositions capable of promoting both the innate immune response as well as the adaptive immune response in a subject based on the jointly use of ApoA, interleukin 15 and the Sushi domain of the IL15 receptor alpha chain, as well as to the use of these compositions for the stimulation of the immune response in a patient and to therapeutic methods for the treatment of infectious and neoplastic diseases.
Public/Granted literature
- US20120244118A1 CONJUGATES AND COMPOSITIONS FOR IMMUNOTHERAPY AND ANTI-TUMORAL TREATMENT Public/Granted day:2012-09-27
Information query
IPC分类:
