Invention Grant
- Patent Title: Biological material suitable for the therapy of osteoarthrosis, ligament damage and for the treatment of joint disorders
- Patent Title (中): 生物材料适用于治疗骨关节炎,韧带损伤和治疗关节疾病
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Application No.: US13380971Application Date: 2010-06-29
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Publication No.: US08771672B2Publication Date: 2014-07-08
- Inventor: Lanfranco Callegaro , Anna Maria Zanellato
- Applicant: Lanfranco Callegaro , Anna Maria Zanellato
- Applicant Address: IT Abano Terme
- Assignee: Fidia Farmaceutici S.p.A.
- Current Assignee: Fidia Farmaceutici S.p.A.
- Current Assignee Address: IT Abano Terme
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: ITMI2009A1171 20090702
- International Application: PCT/EP2010/059183 WO 20100629
- International Announcement: WO2011/000820 WO 20110106
- Main IPC: A61K35/12
- IPC: A61K35/12 ; A61K35/16 ; A61P17/02 ; A61P19/00 ; A61P19/02

Abstract:
The present invention regards a biological material comprising: a) a liquid carrier comprising a viscous solution containing at least one natural and/or semisynthetic polysaccharide, and having a Dynamic viscosity measured at 20° C. and at shear rate of D=350 s−1, comprised between 100 and 250 c Poise and/or a Kinematic viscosity comprised between 99 and 248 cSt (measured at the same conditions); b) a culture of mesenchymal stem cells, and/or c) a platelet-rich hemo-derivative. This type of material in form of viscous liquid is particularly suitable for the therapy of osteoarthrosis, ligament damage, in particular tendon and cartilage damage) and may be administered intra-articularly, intradermally or directly applied in situ without altering the properties of the mesenchymal stem cells and/or platelets contained therein.
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