Invention Grant
- Patent Title: Antibodies directed to HER-3 and uses thereof
- Patent Title (中): 针对HER-3的抗体及其用途
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Application No.: US12761370Application Date: 2010-04-15
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Publication No.: US08771695B2Publication Date: 2014-07-08
- Inventor: Mike Rothe , Martin Treder , Susanne Hartmann , Daniel J. Freeman , Robert Radinsky , Eric Borges
- Applicant: Mike Rothe , Martin Treder , Susanne Hartmann , Daniel J. Freeman , Robert Radinsky , Eric Borges
- Applicant Address: DE US CA Thousand Oaks
- Assignee: U3 Pharma GmbH,Amgen, Inc.
- Current Assignee: U3 Pharma GmbH,Amgen, Inc.
- Current Assignee Address: DE US CA Thousand Oaks
- Agency: Chao Hadidi Stark & Barker LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.
Public/Granted literature
- US20120058122A1 Antibodies Directed to HER-3 and Uses Thereof Public/Granted day:2012-03-08
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