Invention Grant
- Patent Title: Therapeutic vaccination against active Tuberculosis
- Patent Title (中): 针对活动性结核病的治疗性接种
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Application No.: US13822593Application Date: 2011-09-19
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Publication No.: US08771709B2Publication Date: 2014-07-08
- Inventor: Jerald Sadoff , Anisah Alyahya
- Applicant: Jerald Sadoff , Anisah Alyahya
- Applicant Address: NL Leiden
- Assignee: Crucell Holland B.V.
- Current Assignee: Crucell Holland B.V.
- Current Assignee Address: NL Leiden
- Agency: TraskBritt, P.C.
- Priority: EP10177667 20100920
- International Application: PCT/EP2011/066183 WO 20110919
- International Announcement: WO2012/038367 WO 20120329
- Main IPC: A61K39/04
- IPC: A61K39/04 ; A61K49/00 ; A61K39/12
Abstract:
The invention provides a method for therapeutic treatment of a patient having active tuberculosis (TB), the method comprising: administering to the patient a recombinant adenovirus vector that comprises nucleic acid encoding the Ag85A, Ag85B and TB10.4 antigens of Mycobactium tuberculosis (Mtb). Advantageously, the method can be used to shorten conventional drug therapy for treating active TB.
Public/Granted literature
- US20130171193A1 THERAPEUTIC VACCINATION AGAINST ACTIVE TUBERCULOSIS Public/Granted day:2013-07-04
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