Invention Grant
- Patent Title: Microfluidized oil-in-water emulsions and vaccine compositions
- Patent Title (中): 微流化水包油乳剂和疫苗组合物
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Application No.: US12650715Application Date: 2009-12-31
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Publication No.: US08771727B2Publication Date: 2014-07-08
- Inventor: Paul J. Dominowski , Ramasamy M. Mannan , Richard L. Krebs , Pamela K. Klose
- Applicant: Paul J. Dominowski , Ramasamy M. Mannan , Richard L. Krebs , Pamela K. Klose
- Applicant Address: US NJ Florham Park
- Assignee: Zoetis LLC
- Current Assignee: Zoetis LLC
- Current Assignee Address: US NJ Florham Park
- Agent Vyacheslav V. Vasilyev
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K39/02 ; A61K45/00
Abstract:
This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
Public/Granted literature
- US20100173854A1 Microfluidized Oil-in-water Emulsions and Vaccine Compositions Public/Granted day:2010-07-08
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