Invention Grant
- Patent Title: SCDs as modifiers of the p53 pathway and methods of use
- Patent Title (中): SCD作为p53途径的修饰物和使用方法
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Application No.: US12714257Application Date: 2010-02-26
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Publication No.: US08771942B2Publication Date: 2014-07-08
- Inventor: Marcia Belvin , Helen Francis-Lang , Lori Friedman , Gregory D. Plowman , Timothy S. Heuer
- Applicant: Marcia Belvin , Helen Francis-Lang , Lori Friedman , Gregory D. Plowman , Timothy S. Heuer
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Human SCD genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SCD are provided.
Public/Granted literature
- US20100159470A1 SCDs As Modifiers of the p53 Pathway and Methods of Use Public/Granted day:2010-06-24
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