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US08771965B2 Methods and compositions involving nucleotide repeat disorders 有权
涉及核苷酸重复障碍的方法和组合

Methods and compositions involving nucleotide repeat disorders
Abstract:
The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
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