Invention Grant
- Patent Title: Compositions and methods utilizing DNA polymerases
- Patent Title (中): 使用DNA聚合酶的组合物和方法
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Application No.: US11435018Application Date: 2006-05-15
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Publication No.: US08772006B2Publication Date: 2014-07-08
- Inventor: Joseph A. Sorge , Connie Jo Hansen , Holly Hogrefe
- Applicant: Joseph A. Sorge , Connie Jo Hansen , Holly Hogrefe
- Applicant Address: US CO Loveland
- Assignee: Agilent Technologies, Inc.
- Current Assignee: Agilent Technologies, Inc.
- Current Assignee Address: US CO Loveland
- Agency: Fox Rothschild LLP
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12P19/34
Abstract:
The invention features a novel isolated Family B DNA polymerase, a Thermococcus polymerase JDF-3, and mutant recombinant forms thereof. Mutant polymerases of the invention are deficient in 3′ to 5′ exonuclease activity and/or exhibit reduced discrimination against non-conventional nucleotides relative to the wild-type form of the polymerase.
Public/Granted literature
- US20080280291A1 Compositions and methods utilizing DNA polymerases Public/Granted day:2008-11-13
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