Invention Grant
- Patent Title: β-Glucosidase variants
- Patent Title (中): 葡萄糖苷酶变体
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Application No.: US13375189Application Date: 2010-06-16
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Publication No.: US08772010B2Publication Date: 2014-07-08
- Inventor: Xiyun Zhang , Jie Yang , Dipnath Baidyaroy , Sally Rhiannon Postlethwaite , Attila Andor , Louis Clark , Lisa M. Newman
- Applicant: Xiyun Zhang , Jie Yang , Dipnath Baidyaroy , Sally Rhiannon Postlethwaite , Attila Andor , Louis Clark , Lisa M. Newman
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- International Application: PCT/US2010/038902 WO 20100616
- International Announcement: WO2010/148148 WO 20101223
- Main IPC: C12N9/42
- IPC: C12N9/42 ; C12N9/14 ; C12N9/24 ; C12N9/00
Abstract:
The invention relates to recombinantly produced β-Glucosidase Variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue.
Public/Granted literature
- US20120077216A1 Beta-Glucosidase Variants Public/Granted day:2012-03-29
Information query
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