Invention Grant
US08772021B2 Expression vector for animal cell comprising at least one copy of MAR DNA sequences at the 3′ terminal of transcription termination region of a gene and method for the expression of foreign gene using the vector
有权
在基因的转录终止区的3'末端包含至少一个MAR DNA序列拷贝的动物细胞的表达载体和使用载体表达外源基因的方法
- Patent Title: Expression vector for animal cell comprising at least one copy of MAR DNA sequences at the 3′ terminal of transcription termination region of a gene and method for the expression of foreign gene using the vector
- Patent Title (中): 在基因的转录终止区的3'末端包含至少一个MAR DNA序列拷贝的动物细胞的表达载体和使用载体表达外源基因的方法
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Application No.: US11817756Application Date: 2006-03-04
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Publication No.: US08772021B2Publication Date: 2014-07-08
- Inventor: Jong-mook Kim , Hye-jin Hong , Hyun-joo Lee , Moon-kyoung So , Soo-young Lee , Jong-moon Cho , Bok-hwan Chun , Seung-suh Hong , Myung-sam Cho
- Applicant: Jong-mook Kim , Hye-jin Hong , Hyun-joo Lee , Moon-kyoung So , Soo-young Lee , Jong-moon Cho , Bok-hwan Chun , Seung-suh Hong , Myung-sam Cho
- Applicant Address: KR
- Assignee: Celltrion, Inc.
- Current Assignee: Celltrion, Inc.
- Current Assignee Address: KR
- Agency: Cantor Colburn LLP
- Priority: KR10-2005-0018130 20050304
- International Application: PCT/KR2006/000753 WO 20060304
- International Announcement: WO2006/093397 WO 20060908
- Main IPC: C12N15/00
- IPC: C12N15/00

Abstract:
Provided are an expression vector for an animal cell including a promoter, a cloning site or a polynucleotide encoding foreign product, and a transcription terminator, all of which are operably connected each other within the expression vector, in which at least one copy of human β-globin MAR sequence is attached to the 31 terminal of the transcription terminator, and a method of expressing a foreign gene using the expression vector.
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