Invention Grant
- Patent Title: Promoters for recombinant viral expression
- Patent Title (中): 重组病毒表达的启动子
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Application No.: US13131586Application Date: 2009-11-27
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Publication No.: US08772023B2Publication Date: 2014-07-08
- Inventor: Robin Steigerwald , Christine Meisinger-Henschel , Eva Felder
- Applicant: Robin Steigerwald , Christine Meisinger-Henschel , Eva Felder
- Applicant Address: DK Kvistgaard
- Assignee: Bavarian Nordic A/S
- Current Assignee: Bavarian Nordic A/S
- Current Assignee Address: DK Kvistgaard
- Agency: Law Office of Salvatore Arrigo and Scott Lee, LLP
- Priority: EP08020617 20081127
- International Application: PCT/EP2009/008459 WO 20091127
- International Announcement: WO2010/060632 WO 20100603
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A61K39/12

Abstract:
The invention relates to a promoter selected from a group of nucleic acids consisting of (a) a nucleic acid having the nucleotide sequence of SEQ ID NO:1; (b) a nucleic acid having a nucleotide sequence derived from SEQ ID NO:1, wherein not more than 10 nucleotides have been added, deleted, substituted and/or inverted from the nucleic acid of SEQ ID NO:1; and (c) a nucleic acid sequence having at least 70% identity with the nucleic acid of (a); wherein the promoter has a length of up to and including 27 nucleotides and wherein the promoter according to options (b) and (c) exhibits at least the 70% of the promoter activity of SEQ ID NO:1 as measured by the amount of recombinant protein produced.
Public/Granted literature
- US20120121617A1 PROMOTERS FOR RECOMBINANT VIRAL EXPRESSION Public/Granted day:2012-05-17
Information query
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