Invention Grant
US08772025B2 Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
有权
用于灭活α16岩藻糖基转移酶（FUT8）基因表达的方法和组合物
- Patent Title: Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
- Patent Title (中): 用于灭活α16岩藻糖基转移酶（FUT8）基因表达的方法和组合物
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Application No.: US12931265Application Date: 2011-01-27
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Publication No.: US08772025B2Publication Date: 2014-07-08
- Inventor: Trevor Collingwood , Gregory J. Cost
- Applicant: Trevor Collingwood , Gregory J. Cost
- Applicant Address: US CA Richmond
- Assignee: Sangamo BioSciences, Inc.
- Current Assignee: Sangamo BioSciences, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law
- Agent Susan Abrahamson
- Main IPC: C07H17/00
- IPC: C07H17/00 ; C07K14/00
Abstract:
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Public/Granted literature
- US20110159541A1 Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression Public/Granted day:2011-06-30
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