Invention Grant
- Patent Title: Modulation of oocyte meiotic progression and oocyte activation
- Patent Title (中): 调节卵母细胞减数分裂进展和卵母细胞活化
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Application No.: US13548326Application Date: 2012-07-13
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Publication No.: US08772029B2Publication Date: 2014-07-08
- Inventor: Teresa K. Woodruff , Thomas V. O'Halloran , Miranda L. Bernhardt , Betty Y. Kong , Alison M. Kim
- Applicant: Teresa K. Woodruff , Thomas V. O'Halloran , Miranda L. Bernhardt , Betty Y. Kong , Alison M. Kim
- Applicant Address: US IL Evanston
- Assignee: Northwestern University
- Current Assignee: Northwestern University
- Current Assignee Address: US IL Evanston
- Agency: Casimir Jones S.C.
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02
Abstract:
The present invention provides methods, compositions, and systems for reinitiating meiosis in cells in meiotic arrest and oocyte activation in fertilized, but un-activated, oocytes. In certain embodiments, Zn-binding moieties (e.g., zinc chelators) are used for reinitiating meiosis or oocyte activation.
Public/Granted literature
- US20130017602A1 MODULATION OF OOCYTE MEIOTIC PROGRESSION AND OOCYTE ACTIVATION Public/Granted day:2013-01-17
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