A nonwoven wipe having a reversible sanitizer indicator for multiple uses and recharges is provided. The nonwoven wipe includes a cloth-like nonwoven fabric coated with a reversible color-changing ink formulation. During use, the nonwoven wipe is impregnated with a quaternary ammonium compound-based sanitizer. When the level of free quaternary ammonium compound falls below a threshold level, the color-changing ink formulation changes from a first color to a second color, indicating the need to recharge the wipe. When the nonwoven wipe is recharged with sanitizer solution, the color-changing ink formulation changes back to the first color.