Invention Grant
US08772255B2 Cell transfecting formulations of small interfering RNA related compositions and methods of making and use
有权
小干扰RNA相关组合物的细胞转染制剂及制备和使用方法
- Patent Title: Cell transfecting formulations of small interfering RNA related compositions and methods of making and use
- Patent Title (中): 小干扰RNA相关组合物的细胞转染制剂及制备和使用方法
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Application No.: US12053486Application Date: 2008-03-21
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Publication No.: US08772255B2Publication Date: 2014-07-08
- Inventor: Timothy S. Burkoth , Anne B. Jefferson , Christoph Reinhard , Ronald N. Zuckermann
- Applicant: Timothy S. Burkoth , Anne B. Jefferson , Christoph Reinhard , Ronald N. Zuckermann
- Applicant Address: US MA Cambridge
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US MA Cambridge
- Agent Jennifer Wahlsten; Helen Lee
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K47/48
Abstract:
Compositions incorporating small interfering ribonucleic acid (siRNA) and certain lipid-conjugated polyamide compound-based delivery vehicles that are particularly useful in the delivery siRNA and other polynucleotides to cells. Also, methods of making and using the compositions.
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Information query
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