Invention Grant
- Patent Title: Methods for inhibiting expression of connective tissue growth factor
- Patent Title (中): 抑制结缔组织生长因子表达的方法
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Application No.: US13584573Application Date: 2012-08-13
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Publication No.: US08772260B2Publication Date: 2014-07-08
- Inventor: Nicholas M. Dean , J. Gordon Foulkes , Niall O'Donnell , C. Frank Bennett , Susan M. Frier
- Applicant: Nicholas M. Dean , J. Gordon Foulkes , Niall O'Donnell , C. Frank Bennett , Susan M. Frier
- Applicant Address: US CA Carlsbad US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc,Excaliard Pharmaceuticals, Inc
- Current Assignee: Isis Pharmaceuticals, Inc,Excaliard Pharmaceuticals, Inc
- Current Assignee Address: US CA Carlsbad US CA Carlsbad
- Agency: Lando & Anastasi LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12Q1/68
Abstract:
This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.
Public/Granted literature
- US20130190382A1 METHODS FOR INHIBITING EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR Public/Granted day:2013-07-25
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