Invention Grant
- Patent Title: Chemical compounds
- Patent Title (中): 化合物
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Application No.: US13178534Application Date: 2011-07-08
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Publication No.: US08772293B2Publication Date: 2014-07-08
- Inventor: Alan Daniel Brown , Marcel John De Groot , Brian Edward Marron , David James Rawson , Thomas Ryckmans , Robert Ian Storer , Paul Anthony Stupple , Nigel Alan Swain , Christopher William West
- Applicant: Alan Daniel Brown , Marcel John De Groot , Brian Edward Marron , David James Rawson , Thomas Ryckmans , Robert Ian Storer , Paul Anthony Stupple , Nigel Alan Swain , Christopher William West
- Applicant Address: GB Sandwich US NC Durham
- Assignee: Pfizer Limited,Icagen Inc.
- Current Assignee: Pfizer Limited,Icagen Inc.
- Current Assignee Address: GB Sandwich US NC Durham
- Agent J. Michael Dixon
- Main IPC: A01N43/58
- IPC: A01N43/58 ; A61K31/50 ; A01N43/40 ; A61K31/435 ; A01N43/56 ; A61K31/415 ; A01N43/36 ; A61K31/40

Abstract:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I): or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
Public/Granted literature
- US20120010182A1 Chemical Compounds Public/Granted day:2012-01-12
Information query
IPC分类: