Invention Grant
US08772308B2 Non-peptidyl, potent, and selective mu opioid receptor antagonists
有权
非肽，有效和选择性的阿片样物质受体拮抗剂
- Patent Title: Non-peptidyl, potent, and selective mu opioid receptor antagonists
- Patent Title (中): 非肽，有效和选择性的阿片样物质受体拮抗剂
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Application No.: US13144788Application Date: 2010-01-15
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Publication No.: US08772308B2Publication Date: 2014-07-08
- Inventor: Yan Zhang , Dana E. Selley , William Dewey
- Applicant: Yan Zhang , Dana E. Selley , William Dewey
- Applicant Address: US VA Richmond
- Assignee: Virginia Commonwealth University
- Current Assignee: Virginia Commonwealth University
- Current Assignee Address: US VA Richmond
- Agency: Whitham, Curtis, Christofferson & Cook, PC
- International Application: PCT/US2010/021157 WO 20100115
- International Announcement: WO2010/083384 WO 20100722
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/08
Abstract:
Selective, non-peptide antagonists of the mu opioid receptor (MOR) and methods of their use are provided. The antagonists may be used, for example, to identify MOR agonists in competitive binding assays, and to treat conditions related to addiction in which MOR is involved, e.g. heroin, prescription drug and alcohol addiction.
Public/Granted literature
- US20110306628A1 NON-PEPTIDYL, POTENT, AND SELECTIVE MU OPIOID RECEPTOR ANTAGONISTS Public/Granted day:2011-12-15
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