Invention Grant
US08772323B2 Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonists
有权
苯并恶唑和四氢苯并恶唑取代的哒嗪酮作为GPR119激动剂
- Patent Title: Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonists
- Patent Title (中): 苯并恶唑和四氢苯并恶唑取代的哒嗪酮作为GPR119激动剂
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Application No.: US13696094Application Date: 2011-05-06
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Publication No.: US08772323B2Publication Date: 2014-07-08
- Inventor: Matthias Grauert , Remko Bakker , Steffen Breitfelder , Frank Buettner , Peter Eickelmann , Thomas Fox , Marc Grundl , Thorsten Lehmann-Lintz , Wolfgang Rist
- Applicant: Matthias Grauert , Remko Bakker , Steffen Breitfelder , Frank Buettner , Peter Eickelmann , Thomas Fox , Marc Grundl , Thorsten Lehmann-Lintz , Wolfgang Rist
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Timothy X. Witkowski
- Priority: EP10162364 20100507
- International Application: PCT/EP2011/057285 WO 20110506
- International Announcement: WO2011/138427 WO 20111110
- Main IPC: A61K31/423
- IPC: A61K31/423 ; C07D263/54
Abstract:
The present invention relates to pyridazinone derivatives of general formula I, wherein the groups A, G and R1 are as defined in the application, the tautomers thereof, stereoisomers thereof, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.
Public/Granted literature
- US20130172323A1 PYRIDAZINONES AS GPR119 AGONISTS Public/Granted day:2013-07-04
Information query
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