Invention Grant
US08772326B2 Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity
有权
肝细胞生长因子(分散因子)活性的小分子调节剂的方法和组成
- Patent Title: Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity
- Patent Title (中): 肝细胞生长因子(分散因子)活性的小分子调节剂的方法和组成
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Application No.: US13003514Application Date: 2009-07-09
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Publication No.: US08772326B2Publication Date: 2014-07-08
- Inventor: Weizhong Cai , Prakash Narayan , Bijoy Panicker , David E. Smith
- Applicant: Weizhong Cai , Prakash Narayan , Bijoy Panicker , David E. Smith
- Applicant Address: US NY Uiondale
- Assignee: Anigion Biomedica Corp.
- Current Assignee: Anigion Biomedica Corp.
- Current Assignee Address: US NY Uiondale
- Agency: Choate, Hall & Stewart, LLP
- Agent Brenda Herschbach Jarrell; Danielle M. Nihan
- International Application: PCT/US2009/004014 WO 20090709
- International Announcement: WO2010/005580 WO 20100114
- Main IPC: A01N43/56
- IPC: A01N43/56 ; A61K31/415 ; A01N43/00 ; A61K31/55 ; A01N57/00 ; A61K31/675 ; C07D231/00

Abstract:
The present invention provides compositions and formulations of compounds having formula (I) and pharmaceutically acceptable derivatives thereof, wherein p, R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of injuries, conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role. In addition, methods are provided for treating such diseases or diseases starting at a time after the onset of the injury, condition or disease.
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