Invention Grant
US08772328B2 Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
有权
氨基四氢吡喃作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
- Patent Title: Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
- Patent Title (中): 氨基四氢吡喃作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
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Application No.: US14059638Application Date: 2013-10-22
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Publication No.: US08772328B2Publication Date: 2014-07-08
- Inventor: Tesfaye Biftu , Ann E. Weber
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; Anna L. Cocuzzo
- Main IPC: A61K45/06
- IPC: A61K45/06 ; A61K31/4162
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US20140051740A1 AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Public/Granted day:2014-02-20
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