Invention Grant
- Patent Title: Aptamer regulated nucleic acids and uses thereof
- Patent Title (中): 适体调节核酸及其用途
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Application No.: US11884110Application Date: 2006-02-09
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Publication No.: US08772464B2Publication Date: 2014-07-08
- Inventor: Christina D. Smolke , Travis S. Bayer
- Applicant: Christina D. Smolke , Travis S. Bayer
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: McCarter & English, LLP
- Agent Elizabeth A. Hanley; Yu Lu
- International Application: PCT/US2006/004801 WO 20060209
- International Announcement: WO2006/086669 WO 20060817
- Main IPC: C12N15/115
- IPC: C12N15/115 ; C12N15/11 ; C12Q1/25 ; C12Q1/68 ; C12N15/00
Abstract:
The invention relates to aptamer-regulated, ligand-responsive nucleic acids, or “ampliSwitches,” and uses thereof. Particular embodiments include a ligand-responsive nucleic acid that comprises a primer sequence domain and an aptamer domain that is responsive to a ligand.
Public/Granted literature
- US20120035065A1 Aptamer Regulated Nucleic Acids and Uses Thereof Public/Granted day:2012-02-09
Information query
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