Invention Grant
US08772483B2 Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid
有权
固体形式的（S）-2-氨基-3-（4-（2-氨基-6 - （（R）-1-（4-氯-2-（3-甲基-1H-吡唑-1-基） 苯基）-2,2,2-三氟乙氧基）嘧啶-4-基）苯基）丙酸
- Patent Title: Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid
- Patent Title (中): 固体形式的（S）-2-氨基-3-（4-（2-氨基-6 - （（R）-1-（4-氯-2-（3-甲基-1H-吡唑-1-基） 苯基）-2,2,2-三氟乙氧基）嘧啶-4-基）苯基）丙酸
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Application No.: US13288366Application Date: 2011-11-03
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Publication No.: US08772483B2Publication Date: 2014-07-08
- Inventor: Qun Li , Weifeng Hu , Xiaogen Yang , Jiangqiong Zhao , Matthew Mangzhu Zhao
- Applicant: Qun Li , Weifeng Hu , Xiaogen Yang , Jiangqiong Zhao , Matthew Mangzhu Zhao
- Applicant Address: US TX The Woodlands
- Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee Address: US TX The Woodlands
- Agent Max Bachrach
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/506 ; A61P35/00
Abstract:
Solid forms of (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid and salts thereof are disclosed. Pharmaceutical dosage forms and methods of their use are also disclosed.
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