Invention Grant
US08772496B2 Intermediate and process useful in the preparation of {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone
有权
可用于制备{2- [1-（3,5-双 - 三氟甲基 - 苄基）-5-吡啶-4-基-1H- [1,2,3]三唑-4-基] - 吡啶-3-基} - （2-氯苯基） - 甲酮
![Intermediate and process useful in the preparation of {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone](/docs/US/2014-07-08/US08772496B2/abs.jpg.600x600.jpg)
- Patent Title: Intermediate and process useful in the preparation of {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone
- Patent Title (中): 可用于制备{2- [1-（3,5-双 - 三氟甲基 - 苄基）-5-吡啶-4-基-1H- [1,2,3]三唑-4-基] - 吡啶-3-基} - （2-氯苯基） - 甲酮
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Application No.: US12515794Application Date: 2007-12-04
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Publication No.: US08772496B2Publication Date: 2014-07-08
- Inventor: Pingyun Chen
- Applicant: Pingyun Chen
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agency: Hoffman Warnick LLC
- Agent Jayme M. Torelli
- International Application: PCT/US2007/086319 WO 20071204
- International Announcement: WO2008/079600 WO 20080703
- Main IPC: C07D401/14
- IPC: C07D401/14
![Intermediate and process useful in the preparation of {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone](/abs-image/US/2014/07/08/US08772496B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel compounds, (2-chlorophenyl)-[2-(2-hydroxy-2-pyridin-4-yl-vinyl)pyridin-3-yl]methanone benzoate, and (2-chlorophenyl)-[2-(2-hydroxy-2-pyridin-4-yl-vinyl)pyridin-3-yl]methanone toluate, which are useful intermediates for the preparation of the compound of Formula I: (I) The present invention further relates to novel processes for preparing a crystalline compound, which is {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone, Form IV.
Public/Granted literature
- US20100056795A1 NOVEL INTERMEDIATE AND PROCESS USEFUL IN THE PREPARATION OF -(2-CHLOROPHENYL)-METHANONE Public/Granted day:2010-03-04
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