Invention Grant
- Patent Title: PDE10 modulators
- Patent Title (中): PDE10调制器
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Application No.: US13598848Application Date: 2012-08-30
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Publication No.: US08772510B2Publication Date: 2014-07-08
- Inventor: Stephan Bachmann , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- Applicant: Stephan Bachmann , Alexander Flohr , Katrin Groebke Zbinden , Matthias Koerner , Bernd Kuhn , Jens-Uwe Peters , Markus Rudolph
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP11180135 20110906
- Main IPC: C07D249/04
- IPC: C07D249/04 ; C07D233/54 ; C07D231/10 ; C07D207/30
Abstract:
The present invention relates to compounds of formula (I) wherein R1, R2, R3, R5, W, X, X1, Y, Y1, Z and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used in the treatment of CNS disorders such as schizophrenia, Alzheimer's disease, and Parkinson's disease.
Public/Granted literature
- US20130059833A1 PDE10 MODULATORS Public/Granted day:2013-03-07
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