Invention Grant
- Patent Title: Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
- Patent Title (中): 抗增殖化合物，其缀合物，其方法及其应用
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Application No.: US13752721Application Date: 2013-01-29
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Publication No.: US08772543B2Publication Date: 2014-07-08
- Inventor: Heng Cheng , Sanjeev Gangwar , Qiang Cong , Qian Zhang
- Applicant: Medarex, Inc.
- Applicant Address: US NJ Princeton
- Assignee: Medarex, L.L.C.
- Current Assignee: Medarex, L.L.C.
- Current Assignee Address: US NJ Princeton
- Agent Yuan Chao
- Main IPC: C07C235/00
- IPC: C07C235/00 ; C07C237/00 ; C07C239/00 ; C07C211/00
Abstract:
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:
Public/Granted literature
- US20130204033A1 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF Public/Granted day:2013-08-08
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