A maximum voltage selection circuit and method and a sub-selection circuit are provided. The maximum voltage selection circuit includes a peripheral signal circuit and a selection circuit with N channels of input voltages. The peripheral signal circuit provides an operating mode signal and a reference voltage to the selection circuit including N sub-selection circuits coupled to the N channels of input voltages respectively. A sub-selection circuit determines its operating mode according to the operating mode signal. In the operating mode, when an input voltage of a sub-selection circuit is larger than the reference voltage, the sub-selection circuit sets itself to the output enable state and sets other sub-selection circuits to the output disable state, and outputs its input voltage as a maximum voltage through a PMOS.