A method for driving pixels of an active matrix organic light-emitting diode display is disclosed. The method includes charging a first terminal and a second terminal of a first capacitor with a reference voltage and a reset voltage respectively, and turning on a third switch simultaneously, floating the second terminal of the first capacitor, charging the first terminal of the first capacitor according to a data voltage, floating the first terminal of the first capacitor and turning on the third switch. Thus, determine a driving current independent of process variances of the N-type thin film transistor and a voltage drop of an OLED according to a difference voltage across the first capacitor.