A transmitter includes an input, a modulator, and a calibration memory configured to store discrete calibration test points. A compensator is coupled between the input and the modulator and cooperates with the calibration memory to cause the modulator to generate a respective calibration carrier signal for each of the discrete calibration test points during a calibration phase. A detector is coupled to an output of the modulator and is configured to determine respective calibration values of the calibration carrier signals during the calibration phase. A compensator calculator is coupled to an output of the detector, and is configured to generate compensation values for the compensator for use during an operation phase and based on the calibration values of the calibration carrier signals.