Invention Grant
US08778625B2 2-(2-hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors
有权
2-（2-羟基联苯-3-基）-1H-苯并咪唑-5-甲脒衍生物作为因子VIIA抑制剂
- Patent Title: 2-(2-hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors
- Patent Title (中): 2-（2-羟基联苯-3-基）-1H-苯并咪唑-5-甲脒衍生物作为因子VIIA抑制剂
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Application No.: US13607402Application Date: 2012-09-07
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Publication No.: US08778625B2Publication Date: 2014-07-15
- Inventor: Aleksandr Kolesnikov , Roopa Rai , William Dvorak Shrader , Steven M. Torkelson , Kieron E. Wesson , Wendy B. Young
- Applicant: Aleksandr Kolesnikov , Roopa Rai , William Dvorak Shrader , Steven M. Torkelson , Kieron E. Wesson , Wendy B. Young
- Applicant Address: US CA Sunnyvale
- Assignee: Pharmacyclics, Inc.
- Current Assignee: Pharmacyclics, Inc.
- Current Assignee Address: US CA Sunnyvale
- Agency: Wilson, Sinsini, Goodrich & Rosati
- Main IPC: C12Q1/56
- IPC: C12Q1/56
Abstract:
The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
Public/Granted literature
- US20130157298A1 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors Public/Granted day:2013-06-20
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