Invention Grant
- Patent Title: Method for reducing DNA impurities in viral compositions
- Patent Title (中): 减少病毒组合物中DNA杂质的方法
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Application No.: US13813897Application Date: 2010-08-12
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Publication No.: US08778653B2Publication Date: 2014-07-15
- Inventor: Yi Zhang , Jinming Dai , Yajin Ni
- Applicant: Yi Zhang , Jinming Dai , Yajin Ni
- Applicant Address: CN Kaifeng
- Assignee: Yisheng Biopharma Holdings Ltd.
- Current Assignee: Yisheng Biopharma Holdings Ltd.
- Current Assignee Address: CN Kaifeng
- Agency: Bozicevic, Field & Francis, LLP
- Agent Shweta Chandra; Elizabeth A. Alcamo
- International Application: PCT/CN2010/075948 WO 20100812
- International Announcement: WO2012/019354 WO 20120216
- Main IPC: C12N7/02
- IPC: C12N7/02 ; C12N7/06 ; A61K39/12 ; C12N7/00 ; A61K39/00

Abstract:
A method for purification of viral compositions is provided. In particular, a method for reduction of unwanted residual DNA in a viral composition while retaining the immunogenicity of the virus itself is provided. The resulting immunogenic viral composition is substantially free of residual DNA, and is useful for the manufacture of medical products, such as vaccines designed for human or animal.
Public/Granted literature
- US20130203152A1 Method for Reducing DNA Impurities in Viral Compositions Public/Granted day:2013-08-08
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