Invention Grant
US08778670B2 Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins
有权
用于切片切片和归巢核酸和蛋白质的细胞的制备方法和装置
- Patent Title: Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins
- Patent Title (中): 用于切片切片和归巢核酸和蛋白质的细胞的制备方法和装置
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Application No.: US13239444Application Date: 2011-09-22
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Publication No.: US08778670B2Publication Date: 2014-07-15
- Inventor: Andrew H. Fischer
- Applicant: Andrew H. Fischer
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12M1/12
- IPC: C12M1/12 ; G01N1/31

Abstract:
A method and apparatus for embedding cells that utilizes a flow-through embedding technique. The apparatus includes a cell flow pathway defined by an inflow tube for delivering cell fragments from a cell sample to a sample port. The sample port is in fluid communication with a tissue cassette having attached thereto a filter. The cell flow pathway is in communication with a reagent flow pathway for delivering the reagents through the sample port to the cassette. The apparatus is configured such that the application of pressure directs the cell fragments from the cell sample through the cell flow pathway, and effects delivery of the reagents through the reagent flow pathway. The apparatus produces an embedded cell block having concentrated cells near the plane of the block to be sectioned in a quick and efficient manner.
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