Invention Grant
US08778671B2 Construction of West Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by West Nile virus
有权
建立西尼罗病毒和登革热病毒嵌合体,用于活病毒疫苗,以预防西尼罗病毒引起的疾病
- Patent Title: Construction of West Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by West Nile virus
- Patent Title (中): 建立西尼罗病毒和登革热病毒嵌合体,用于活病毒疫苗,以预防西尼罗病毒引起的疾病
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Application No.: US10871775Application Date: 2004-06-18
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Publication No.: US08778671B2Publication Date: 2014-07-15
- Inventor: Alexander G. Pletnev , Joseph R. Putnak , Robert M. Chanock , Brian R. Murphy , Stephen S. Whitehead , Joseph E. Blaney, Jr.
- Applicant: Alexander G. Pletnev , Joseph R. Putnak , Robert M. Chanock , Brian R. Murphy , Stephen S. Whitehead , Joseph E. Blaney, Jr.
- Applicant Address: US DC Washington US MD Silver Spring
- Assignee: The United States of America, as represented by the Secretary of the Department of Health & Human Services,The Walter Reed Army Institute of Research
- Current Assignee: The United States of America, as represented by the Secretary of the Department of Health & Human Services,The Walter Reed Army Institute of Research
- Current Assignee Address: US DC Washington US MD Silver Spring
- Agency: Edwards Wildman Palmer LLP
- Agent Peter F. Corless; Richard B. Emmons
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K39/00

Abstract:
The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines.
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