Invention Grant
- Patent Title: Optical based delivery of exogenous molecules to cells
- Patent Title (中): 将外源性分子光学传递给细胞
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Application No.: US13221161Application Date: 2011-08-30
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Publication No.: US08778682B2Publication Date: 2014-07-15
- Inventor: Vasile Bogdan Neculaes , Kenneth Roger Conway , Allen Lawrence Garner , Evelina Roxana Loghin , Siavash Yazdanfar , Dmitry Vladimirovich Dylov , Brian Michael Davis , Chulmin Joo
- Applicant: Vasile Bogdan Neculaes , Kenneth Roger Conway , Allen Lawrence Garner , Evelina Roxana Loghin , Siavash Yazdanfar , Dmitry Vladimirovich Dylov , Brian Michael Davis , Chulmin Joo
- Applicant Address: US NY Niskayuna
- Assignee: General Electric Company
- Current Assignee: General Electric Company
- Current Assignee Address: US NY Niskayuna
- Agent Jenifer E. Haeckl
- Main IPC: C12N15/87
- IPC: C12N15/87 ; C12N13/00
Abstract:
A method of delivering exogenous molecules, comprising: providing a plurality of cells having a cell membrane; adding a plurality of exogenous molecules to the cells; exposing the cells to a defocused infrared (IR) light to permeabilize the cell membrane of the cells; and delivering the exogenous molecules to the cells through the permeablized cell membrane, wherein an intensity of the IR light at the optical focus is at least greater than or equal to an order of 104 W/cm2.
Public/Granted literature
- US20130052738A1 OPTICAL BASED DELIVERY OF EXOGENOUS MOLECULES TO CELLS Public/Granted day:2013-02-28
Information query
IPC分类:
