Invention Grant
US08778972B2 5-pyridin-3-yl-1, 3-dihydro-indol-2-on derivatives and their use as modulators of aldosterone synthase and/or CYP11B1
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5-吡啶-3-基-1,3-二氢 - 吲哚-2-酮衍生物及其作为醛固酮合酶和/或CYP11B1的调节剂的用途
- Patent Title: 5-pyridin-3-yl-1, 3-dihydro-indol-2-on derivatives and their use as modulators of aldosterone synthase and/or CYP11B1
- Patent Title (中): 5-吡啶-3-基-1,3-二氢 - 吲哚-2-酮衍生物及其作为醛固酮合酶和/或CYP11B1的调节剂的用途
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Application No.: US13319786Application Date: 2010-05-12
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Publication No.: US08778972B2Publication Date: 2014-07-15
- Inventor: Qi-Ying Hu , Sylvie Chamoin , Christopher M. Adams , Chun Zhang
- Applicant: Qi-Ying Hu , Sylvie Chamoin , Christopher M. Adams , Chun Zhang
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Sophie Binet Cross
- International Application: PCT/EP2010/056569 WO 20100512
- International Announcement: WO2010/130794 WO 20101118
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/04
Abstract:
The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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