Invention Grant
US08778974B2 Trisubstituted 1,2,4 triazoles 有权
三取代的1,2,4-三唑

Trisubstituted 1,2,4 triazoles
Abstract:
The present invention relates to 1-aryl-3-aniline-5-alkyl-1,2,4-triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to potent positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
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