Invention Grant
US08779158B2 Trisubstituted pyrazoles as acetylcholine receptor modulators 有权
三取代吡唑作为乙酰胆碱受体调节剂

Trisubstituted pyrazoles as acetylcholine receptor modulators
Abstract:
The present invention relates to 1-alkyl-3-aniline-5-aryl-pyrazole derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I).The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.
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