Invention Grant
US08779231B2 Transgenic mouse for expressing human ferritin in tissue non-specific manner and use thereof
有权
用于以组织非特异性方式表达人铁蛋白的转基因小鼠及其用途
- Patent Title: Transgenic mouse for expressing human ferritin in tissue non-specific manner and use thereof
- Patent Title (中): 用于以组织非特异性方式表达人铁蛋白的转基因小鼠及其用途
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Application No.: US13807879Application Date: 2011-07-07
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Publication No.: US08779231B2Publication Date: 2014-07-15
- Inventor: Woo Kyung Moon , Hoe Suk Kim
- Applicant: Woo Kyung Moon , Hoe Suk Kim
- Applicant Address: KR Seoul
- Assignee: SNU R&DB Foundation
- Current Assignee: SNU R&DB Foundation
- Current Assignee Address: KR Seoul
- Agency: Casimir Jones, S.C.
- Agent Tanya A. Arenson
- Priority: KR10-2010-0065413 20100707
- International Application: PCT/KR2011/004983 WO 20110707
- International Announcement: WO2012/005529 WO 20120112
- Main IPC: A01K67/00
- IPC: A01K67/00 ; C12N15/00
Abstract:
The present invention relates to a recombinant vector and a transgenic mouse for expressing human ferritin in a tissue non-specific manner, and more particularly, to a vector prepared by operably linking a human ferritin gene to a promoter including a cytomegalovirus (CMV) early enhancer element and a β-actin promoter, and a transgenic mouse expressing human ferritin in a tissue non-specific manner, which is transformed with the vector. Further, the present invention relates to a method for preparing a transgenic mouse, and a method for monitoring cell or tissue therapy using the transgenic mouse.
Public/Granted literature
- US20130174284A1 TRANSGENIC MOUSE FOR EXPRESSING HUMAN FERRITIN IN TISSUE NON-SPECIFIC MANNER AND USE THEREOF Public/Granted day:2013-07-04
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