Invention Grant
- Patent Title: Artificial binding proteins based on ubiquitin
- Patent Title (中): 基于泛素的人工结合蛋白
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Application No.: US12072959Application Date: 2008-02-29
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Publication No.: US08791238B2Publication Date: 2014-07-29
- Inventor: Markus Fiedler , Ulrike Fiedler , Rainer Rudolph
- Applicant: Markus Fiedler , Ulrike Fiedler , Rainer Rudolph
- Applicant Address: DE Halle-Saale
- Assignee: Scil Proteins GmbH
- Current Assignee: Scil Proteins GmbH
- Current Assignee Address: DE Halle-Saale
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Priority: DE10324447 20030528
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C12N15/10 ; C07K14/00 ; C40B40/02 ; G01N33/68
Abstract:
The invention relates to modified proteins of the superfamily of “ubiquitin-like proteins”, proteins that have a ubiquitin-like fold and fragments or fusion proteins thereof. As a result of said modification, the proteins have a binding affinity with respect to a predetermined binding partner that did not exist previously. The invention also relates to a method for the production and utilization of said proteins.
Public/Granted literature
- US20080171851A1 Generation of artificial binding proteins on the basis of ubiquitin proteins Public/Granted day:2008-07-17
Information query
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