Methods and systems for monitoring a transducer array in an ultrasound probe are provided. One method includes acquiring ultrasound data using an ultrasound probe during an imaging mode of operation, wherein the ultrasound data includes echo information. The method further includes comparing the echo information from a plurality of transducer elements of a transducer array of the ultrasound probe during the imaging mode of operation, wherein the echo information is non-beamformed signal data. The method also includes determining non-uniformity information for the transducer array using the compared echo information during the imaging mode of operation.