A method and apparatus for supporting mobility of a mobile terminal in a Visible Light Communication (VLC) system. The method includes searching, by the VLC device, for a first mobile terminal in a plurality of cells; locating the first mobile terminal in a first cell among the plurality of cells; exchanging data with the first mobile using a light source of the first cell; determining whether a response signal corresponding to data reception is received from the first mobile terminal in the first cell; searching for the first mobile terminal in a neighboring cell of the first cell, if the response signal is not received; and determining the neighboring cell as a second cell for visible light activation, if the first mobile terminal is located in the neighboring cell.