Invention Grant
US08792960B2 Magnetic resonance method and apparatus for automated analysis of joint inflammation, joint proteoglycan proportion, and joint osteoarthritis
有权
用于自发分析关节炎症,关节蛋白聚糖比例和关节骨关节炎的磁共振方法和装置
- Patent Title: Magnetic resonance method and apparatus for automated analysis of joint inflammation, joint proteoglycan proportion, and joint osteoarthritis
- Patent Title (中): 用于自发分析关节炎症,关节蛋白聚糖比例和关节骨关节炎的磁共振方法和装置
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Application No.: US12710869Application Date: 2010-02-23
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Publication No.: US08792960B2Publication Date: 2014-07-29
- Inventor: Timothy Hughes , Tallal Charles Mamisch
- Applicant: Timothy Hughes , Tallal Charles Mamisch
- Applicant Address: DE Munich CH Bern
- Assignee: Siemens Aktiengesellschaft,Inselspital-Stiftung
- Current Assignee: Siemens Aktiengesellschaft,Inselspital-Stiftung
- Current Assignee Address: DE Munich CH Bern
- Agency: Schiff Hardin LLP
- Priority: DE102009010175 20090223
- Main IPC: A61B5/055
- IPC: A61B5/055 ; A61K49/06 ; G01R33/56 ; G01R33/20

Abstract:
In a magnetic resonance method and apparatus for generating an analysis of an inflammation of a joint, for determining a proteoglycan proportion of a joint, and for generating an analysis of osteoarthritis of a joint, for a predetermined region within a body of a patient, a three-dimensional MR image data set is generated with a magnetic resonance imaging scanner. At least, a portion of a joint is located within the region. For each of several different automatically determined layers, a two-dimensional MR image is calculated from the three-dimensional MR image data set. For each layer, the thickness of a predetermined tissue, which is represented in the two-dimensional MR image corresponding to the layer, is determined, by means of which an analysis of a joint inflammation is automatically determined depending on the respective thicknesses. A further layer in the region is also automatically determined and, after injecting a contrast medium, a two-dimensional T1-weighted MR image is generated for this layer, from which a proteoglycan proportion is automatically determined. From the analysis of the joint inflammation and the proteoglycan proportion, it is then possible to perform a reproducible analysis of osteoarthritis of the joint.
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