The invention refers to a method and an element for biasing a cartridge in a drug delivery device. The element for biasing the cartridge in a cartridge housing of a drug delivery device and an according system comprising the element and the drug delivery device are provided which is a self retained element comprising a first member having a shape that allows passage of a spindle of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge housing. This cartridge could be a removable cartridge.