A working mechanism for a medical manipulator and a cleaning method therefor are provided. A working unit of a medical manipulator is equipped with a hollow connecting shaft, wires of a motive force transmitting member disposed in the connecting shaft, and a distal end working unit disposed on one end of the connecting shaft and which is moved by the wires. A cover covers at least a portion of the distal end working unit. A gap is provided between the cover and the connecting shaft, with oblong holes being disposed laterally on right and left sides of the cover. A cleaning agent is made to flow through the holes and the gap and/or a brush may be inserted through the holes and the gap for cleaning the distal end working unit.