Invention Grant
- Patent Title: Treatment of liver disorders by administration of RAP conjugates
- Patent Title (中): 通过施用RAP偶联物治疗肝脏疾病
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Application No.: US12441618Application Date: 2007-09-18
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Publication No.: US08795627B2Publication Date: 2014-08-05
- Inventor: Christopher M. Starr , Todd C. Zankel
- Applicant: Christopher M. Starr , Todd C. Zankel
- Applicant Address: US CA Novato
- Assignee: Raptor Pharmaceuticals Inc.
- Current Assignee: Raptor Pharmaceuticals Inc.
- Current Assignee Address: US CA Novato
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2007/078792 WO 20070918
- International Announcement: WO2008/036682 WO 20080327
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K38/17 ; A61K47/48
Abstract:
The present invention relates to the use of receptor-associate protein (RAP) and fragments and variants thereof to improve delivery of therapeutic compounds to the liver and provides methods to treat liver disorders and conditions, such as hepatic carcinoma, by administering RAP or RAP variants conjugated to active agents.
Public/Granted literature
- US20120251444A1 TREATMENT OF LIVER DISORDERS BY ADMINISTRATION OF RAP CONJUGATES Public/Granted day:2012-10-04
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