Invention Grant
US08795734B2 Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
有权
疏水性纳米管和纳米粒子作为将药物递送到细胞中的转运蛋白
- Patent Title: Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
- Patent Title (中): 疏水性纳米管和纳米粒子作为将药物递送到细胞中的转运蛋白
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Application No.: US13566740Application Date: 2012-08-03
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Publication No.: US08795734B2Publication Date: 2014-08-05
- Inventor: Hongjie Dai , Nadine Wong Shi Kam , Paul A. Wender , Zhuang Liu
- Applicant: Hongjie Dai , Nadine Wong Shi Kam , Paul A. Wender , Zhuang Liu
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agent David J. Aston; Peters Verny, LLP
- Main IPC: A61K9/16
- IPC: A61K9/16 ; A61K9/50 ; A61K38/54 ; A61K39/00 ; B82Y5/00 ; C12N15/11 ; A61K48/00
Abstract:
Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.
Public/Granted literature
- US20130034610A1 HYDROPHOBIC NANOTUBES AND NANOPARTICLES AS TRANSPORTERS FOR THE DELIVERY OF DRUGS INTO CELLS Public/Granted day:2013-02-07
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