Invention Grant
- Patent Title: Increasing bacterial succinate productivity
- Patent Title (中): 增加细菌琥珀酸盐生产力
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Application No.: US13696268Application Date: 2011-05-03
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Publication No.: US08795991B2Publication Date: 2014-08-05
- Inventor: Ka-Yiu San , George Bennett , Grant Balzer , Jiangfeng Zhu , Chandresh Thakker , Ailen Sanchez
- Applicant: Ka-Yiu San , George Bennett , Grant Balzer , Jiangfeng Zhu , Chandresh Thakker , Ailen Sanchez
- Applicant Address: US TX Houston
- Assignee: William Marsh Rice University
- Current Assignee: William Marsh Rice University
- Current Assignee Address: US TX Houston
- Agency: Boulware & Valoir
- International Application: PCT/US2011/035001 WO 20110503
- International Announcement: WO2011/140088 WO 20111110
- Main IPC: C12N15/70
- IPC: C12N15/70
Abstract:
Improved bacteria for making succinate and other 4 carbon dicarboxylates from the Krebs cycle have modifications to reduce acetate, lactate, EtOH and formate, as well as turn on the glyoxylate shunt, produce more NADH and overexpress In one embodiment, the bacteria are ΔadhEΔldhAΔiclRΔack-pta plus PYC+ and NAD+-dependant FDH+.
Public/Granted literature
- US20130203137A1 INCREASING BACTERIAL SUCCINATE PRODUCTIVITY Public/Granted day:2013-08-08
Information query
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