Invention Grant
- Patent Title: Method for treating systemic DNA mutation disease
- Patent Title (中): 全身DNA突变疾病的治疗方法
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Application No.: US13772499Application Date: 2013-02-21
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Publication No.: US08796004B2Publication Date: 2014-08-05
- Inventor: Dmitry Dmitrievich Genkin , Georgy Viktorovich Tets , Viktor Veniaminovich Tets
- Applicant: CLS Therapeutics Limited
- Applicant Address: GB Guernsey, Channels Islands
- Assignee: CLS Therapeutics Limited
- Current Assignee: CLS Therapeutics Limited
- Current Assignee Address: GB Guernsey, Channels Islands
- Agency: Troutman Sanders LLP
- Priority: RUPCT/RU2003/000304 20030714; RU2004108057 20040312
- Main IPC: C12Q1/34
- IPC: C12Q1/34 ; A61K38/46 ; C12N9/16 ; C07K14/00

Abstract:
The invention is directed to treatment of systemic DNA mutation diseases accompanied with development of somatic mosaicism and elevation of blood extracellular DNA. The inventive method comprises introducing a DNASE enzyme into the systemic blood circulation of a patient in doses and regimens which are sufficient to decrease average molecular weight of circulating extracellular blood DNA in the blood of said patient.
Public/Granted literature
- US20130183283A1 Method for Treating Systemic DNA Mutation Disease Public/Granted day:2013-07-18
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